4al8: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4al8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AL8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AL8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4al8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AL8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AL8 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ala|4ala]], [[4am0|4am0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ala|4ala]], [[4am0|4am0]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4al8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4al8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4al8 RCSB], [http://www.ebi.ac.uk/pdbsum/4al8 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4al8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4al8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4al8 RCSB], [http://www.ebi.ac.uk/pdbsum/4al8 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q8BE57_9FLAV Q8BE57_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Dengue virus]] | [[Category: Dengue virus]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Flanagan, A | [[Category: Flanagan, A]] | ||
[[Category: Grimes, J M | [[Category: Grimes, J M]] | ||
[[Category: Midgley, C M | [[Category: Midgley, C M]] | ||
[[Category: Mongkolsapaya, J | [[Category: Mongkolsapaya, J]] | ||
[[Category: Screaton, G R | [[Category: Screaton, G R]] | ||
[[Category: Antibody]] | [[Category: Antibody]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Neutralisation]] | [[Category: Neutralisation]] | ||
