4d2q: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4d2q]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D2Q FirstGlance]. <br> | <table><tr><td colspan='2'>[[4d2q]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D2Q FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d2u|4d2u]], [[4d2x|4d2x]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d2u|4d2u]], [[4d2x|4d2x]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d2q RCSB], [http://www.ebi.ac.uk/pdbsum/4d2q PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d2q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d2q RCSB], [http://www.ebi.ac.uk/pdbsum/4d2q PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CLPB_ECOLI CLPB_ECOLI]] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10982797</ref> <ref>PMID:12624113</ref> <ref>PMID:14640692</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bukau, B | [[Category: Bukau, B]] | ||
[[Category: Carroni, M | [[Category: Carroni, M]] | ||
[[Category: Clare, D K | [[Category: Clare, D K]] | ||
[[Category: Kopp, J | [[Category: Kopp, J]] | ||
[[Category: Kummer, E | [[Category: Kummer, E]] | ||
[[Category: Mogk, A | [[Category: Mogk, A]] | ||
[[Category: Oguchi, Y | [[Category: Oguchi, Y]] | ||
[[Category: Saibil, H R | [[Category: Saibil, H R]] | ||
[[Category: Sinning, I | [[Category: Sinning, I]] | ||
[[Category: Wendler, P | [[Category: Wendler, P]] | ||
[[Category: Bap]] | [[Category: Bap]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
