Chaperones: Difference between revisions
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== Disease == | == Disease == | ||
Chaperones are instrumental in protein folding processes. Alteration in this process may lead to protein aggregation and formation of inclusion bodies. Protein misfolding may result in various diseases such as Alzheimer <ref>PMID:16048838</ref>, Parkinson <ref>PMID:16610362</ref>, Familial amyotrophic lateral sclerosis <ref>doi:10.1002/prca.200780023</ref>, Huntington<ref>PMID:24323530</ref, Spinocerebellar ataxia 1, 2, 3 <ref>doi:10.1016/B978-0-444-51892-7.00027-9</ref>, Spinobulbar muscular atrophy <ref>doi: 10.1093/hmg/11.5.515</ref> and ageing <ref>doi:10.1111/j.1742-4658.2006.05181.x</ref>. | Chaperones are instrumental in protein folding processes. Alteration in this process may lead to protein aggregation and formation of inclusion bodies. Protein misfolding may result in various diseases such as Alzheimer <ref>PMID:16048838</ref>, Parkinson <ref>PMID:16610362</ref>, Familial amyotrophic lateral sclerosis <ref>doi:10.1002/prca.200780023</ref>, Huntington<ref>PMID:24323530</ref>, Spinocerebellar ataxia 1, 2, 3 <ref>doi:10.1016/B978-0-444-51892-7.00027-9</ref>, Spinobulbar muscular atrophy <ref>doi: 10.1093/hmg/11.5.515</ref> and ageing <ref>doi:10.1111/j.1742-4658.2006.05181.x</ref>. | ||
== Relevance == | == Relevance == | ||
