4qfr: Difference between revisions

Line 1:

'''~~Unreleased~~ structure'''

==Structure of AMPK in complex with Cl-A769662 activator and STAUROSPORINE inhibitor==

~~The entry~~ 4qfr ~~is ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4qfr]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QFR OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QFR FirstGlance].

~~Authors~~: Calabrese, M.F., Kurumbail, R.G.

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=32J:2-CHLORO-4-HYDROXY-3-(2-HYDROXYBIPHENYL-4-YL)-6-OXO-6,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE'>32J</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=STU:STAUROSPORINE'>STU</scene>

<tr><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>

~~Description~~:

<tr><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4qfg|4qfg]], [[4qfs|4qfs]]</td></tr>

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qfr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qfr RCSB], [http://www.ebi.ac.uk/pdbsum/4qfr PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Calabrese, M F.]]

[[Category: Kurumbail, R G.]]

[[Category: Ampk]]

[[Category: Cbm]]

[[Category: Kinase]]

[[Category: Signaling protein-inhibitor-activator complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Structure of AMPK in complex with Cl-A769662 activator and STAUROSPORINE inhibitor==
+<StructureSection load='4qfr' size='340' side='right' caption='[[4qfr]], [[Resolution|resolution]] 3.34&Aring;' scene=''>
-The entry 4qfr is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4qfr]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QFR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QFR FirstGlance]. <br>
-Authors: Calabrese, M.F., Kurumbail, R.G.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=32J:2-CHLORO-4-HYDROXY-3-(2-HYDROXYBIPHENYL-4-YL)-6-OXO-6,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE'>32J</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=STU:STAUROSPORINE'>STU</scene><br>
+<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
-Description:
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qfg|4qfg]], [[4qfs|4qfs]]</td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qfr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qfr RCSB], [http://www.ebi.ac.uk/pdbsum/4qfr PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: Calabrese, M F.]]
+[[Category: Kurumbail, R G.]]
+[[Category: Ampk]]
+[[Category: Cbm]]
+[[Category: Kinase]]
+[[Category: Signaling protein-inhibitor-activator complex]]