4q33: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4q33]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q33 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q33 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4q33]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q33 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q33 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YA:4-[(1R)-1-[1-(4-CHLOROPHENYL)-1,2,3-TRIAZOL-4-YL]ETHOXY]-1-OXIDANYL-QUINOLINE'>2YA</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YA:4-[(1R)-1-[1-(4-CHLOROPHENYL)-1,2,3-TRIAZOL-4-YL]ETHOXY]-1-OXIDANYL-QUINOLINE'>2YA</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q32|4q32]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q32|4q32]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q33 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q33 RCSB], [http://www.ebi.ac.uk/pdbsum/4q33 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q33 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q33 RCSB], [http://www.ebi.ac.uk/pdbsum/4q33 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q0TN42_CLOP1 Q0TN42_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: IMP dehydrogenase]] | [[Category: IMP dehydrogenase]] | ||
[[Category: Anderson, W F | [[Category: Anderson, W F]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Gollapalli, D R | [[Category: Gollapalli, D R]] | ||
[[Category: Gorla, S K | [[Category: Gorla, S K]] | ||
[[Category: Gu, M | [[Category: Gu, M]] | ||
[[Category: Hedstrom, L | [[Category: Hedstrom, L]] | ||
[[Category: Joachimiak, A | [[Category: Joachimiak, A]] | ||
[[Category: Kim, Y | [[Category: Kim, Y]] | ||
[[Category: Makowska-Grzyska, M | [[Category: Makowska-Grzyska, M]] | ||
[[Category: Maltseva, N | [[Category: Maltseva, N]] | ||
[[Category: Mandapati, K | [[Category: Mandapati, K]] | ||
[[Category: Mulligan, R | [[Category: Mulligan, R]] | ||
[[Category: Zhang, M | [[Category: Zhang, M]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Dehydrogenase]] | [[Category: Dehydrogenase]] | ||
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[[Category: Niaid]] | [[Category: Niaid]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Tim barrel]] | [[Category: Tim barrel]] | ||
