2mit: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Solution structure of oxidized dimeric form of human defensin 5==

~~The entry~~ 2mit is ~~ON HOLD until sometime in~~ the ~~future~~

== Structural highlights ==

<table><tr><td colspan='2'>[[2mit]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIT FirstGlance]. <br>

~~Authors~~: ~~Wommack~~, A.J., ~~Ziarek~~, J.J., Wagner, G., ~~Nolan~~, ~~E.M.~~

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2lxz|2lxz]], [[1zmp|1zmp]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mit OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mit RCSB], [http://www.ebi.ac.uk/pdbsum/2mit PDBsum]</span></td></tr>

~~Description~~: ~~Solution structure of oxidized dimeric form of human defensin 5~~

</table>

== Function ==

[[http://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN]] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Nolan, E M]]

[[Category: Wagner, G]]

[[Category: Wommack, A J]]

[[Category: Ziarek, J J]]

[[Category: Antimicrobial peptide]]

[[Category: Antimicrobial protein]]

[[Category: Cysteine knot]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Solution structure of oxidized dimeric form of human defensin 5==
+<StructureSection load='2mit' size='340' side='right' caption='[[2mit]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-The entry 2mit is ON HOLD  until sometime in the future
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2mit]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIT FirstGlance]. <br>
-Authors: Wommack, A.J., Ziarek, J.J., Wagner, G., Nolan, E.M.
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2lxz|2lxz]], [[1zmp|1zmp]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mit OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mit RCSB], [http://www.ebi.ac.uk/pdbsum/2mit PDBsum]</span></td></tr>
-Description: Solution structure of oxidized dimeric form of human defensin 5
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN]] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Nolan, E M]]
+[[Category: Wagner, G]]
+[[Category: Wommack, A J]]
+[[Category: Ziarek, J J]]
+[[Category: Antimicrobial peptide]]
+[[Category: Antimicrobial protein]]
+[[Category: Cysteine knot]]