4crn: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4crn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CRN FirstGlance]. <br> | <table><tr><td colspan='2'>[[4crn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CRN FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4crm|4crm]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4crm|4crm]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4crn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4crn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4crn RCSB], [http://www.ebi.ac.uk/pdbsum/4crn PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4crn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4crn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4crn RCSB], [http://www.ebi.ac.uk/pdbsum/4crn PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/ERF3_YEAST ERF3_YEAST]] Involved in translation termination. Stimulates the activity of ERF1. Binds guanine nucleotides. Recruited by polyadenylate-binding protein PAB1 to poly(A)-tails of mRNAs. Interaction with PAB1 is also required for regulation of normal mRNA decay through translation termination-coupled poly(A) shortening.<ref>PMID:7556078</ref> <ref>PMID:12923185</ref> <ref>PMID:15337765</ref> [[http://www.uniprot.org/uniprot/ERF1_YEAST ERF1_YEAST]] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (By similarity).<ref>PMID:7556078</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Barrio-Garcia, C | [[Category: Barrio-Garcia, C]] | ||
[[Category: Becker, T | [[Category: Becker, T]] | ||
[[Category: Beckmann, R | [[Category: Beckmann, R]] | ||
[[Category: Berninghausen, O | [[Category: Berninghausen, O]] | ||
[[Category: Eyler, D | [[Category: Eyler, D]] | ||
[[Category: Green, R | [[Category: Green, R]] | ||
[[Category: Hauser, A | [[Category: Hauser, A]] | ||
[[Category: Heue, A | [[Category: Heue, A]] | ||
[[Category: Preis, A | [[Category: Preis, A]] | ||
[[Category: Cryo-em]] | [[Category: Cryo-em]] | ||
[[Category: Termination]] | [[Category: Termination]] | ||
[[Category: Translation]] | [[Category: Translation]] | ||
Revision as of 21:21, 25 December 2014
Cryo-EM of a pretermination complex with eRF1 and eRF3
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