4pao: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4pao]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PAO FirstGlance]. <br> | <table><tr><td colspan='2'>[[4pao]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PAO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PAO FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pan|4pan]], [[4pam|4pam]], [[4paq|4paq]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pan|4pan]], [[4pam|4pam]], [[4paq|4paq]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pao OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pao RCSB], [http://www.ebi.ac.uk/pdbsum/4pao PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pao OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pao RCSB], [http://www.ebi.ac.uk/pdbsum/4pao PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/GNAI1_RAT GNAI1_RAT]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:16870394</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Gilbert, J | [[Category: Gilbert, J]] | ||
[[Category: Hamm, H E | [[Category: Hamm, H E]] | ||
[[Category: Iverson, T M | [[Category: Iverson, T M]] | ||
[[Category: Kaya, A I | [[Category: Kaya, A I]] | ||
[[Category: Lokits, A D | [[Category: Lokits, A D]] | ||
[[Category: Meiler, J | [[Category: Meiler, J]] | ||
[[Category: Activation of heterotrimeric g protein gdp release]] | [[Category: Activation of heterotrimeric g protein gdp release]] | ||
[[Category: Computer modeling]] | [[Category: Computer modeling]] | ||
