1d96: Difference between revisions

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|PDB= 1d96 |SIZE=350|CAPTION= <scene name='initialview01'>1d96</scene>, resolution 2.000&Aring;
|PDB= 1d96 |SIZE=350|CAPTION= <scene name='initialview01'>1d96</scene>, resolution 2.000&Aring;
|SITE=  
|SITE=  
|LIGAND=  
|LIGAND= <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d96 OCA], [http://www.ebi.ac.uk/pdbsum/1d96 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1d96 RCSB]</span>
}}
}}


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[[Category: double helix]]
[[Category: double helix]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:34:43 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:37:01 2008''

Revision as of 16:37, 30 March 2008

File:1d96.gif


Drag the structure with the mouse to rotate
1d96, resolution 2.000Å
Ligands: C, DA, DC, DG, DT, G
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA


Overview

The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA hybrid segments surrounding a central region of double helical DNA; its molecular structure has been solved by X-ray analysis. All three parts of the molecule adopt a conformation which is close to that seen in the 11-fold RNA double helix. The conformation of the ribonucleotides is partly determined by water molecules bridging between the ribose O2' hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no structural discontinuities. However, the central DNA TATA sequence has some structural irregularities.

About this Structure

1D96 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:6181416

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