Fibrin: Difference between revisions

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{{STRUCTURE_1n73|  PDB=1n73  | SIZE=400| SCENE=Fibrin/Cv/2 |right|CAPTION=Fibrin α1 subunit (red, yellow), β subunit (Green, blue), γ subunit (orange, magenta) from ''Petromyzon marinus'', [[1n73]] }}
{{STRUCTURE_1n73|  PDB=1n73  | SIZE=400| SCENE=Fibrin/Cv/2 |right|CAPTION=Fibrin α1 subunit (red, yellow), β subunit (Green, blue), γ subunit (orange, magenta) from ''Petromyzon marinus'', [[1n73]] }}


[[Fibrin]] (or Factor Ia, FIa) is a fibrous protein which when polymerized is involved in blood clotting. The polymerization epitopes of FIa are called A-knob and B-knob.  [[Fibrinogen]] (Factor I, FI) is converted by thrombin to fibrin.  Limited proteolysis of FI results in a fragment named D which when cross-linked by factor XIII is called double-D FIa (DDFIa). The images at the left and at the right correspond to one representative Fibrin, ''i.e.'' the crystal structure of Fibrin from ''Petromyzon marinus'' ([[1n73]]).
[[Fibrin]] (or Factor Ia, FIa) is a fibrous protein which when polymerized is involved in blood clotting. The polymerization epitopes of FIa are called A-knob and B-knob.  [[Fibrinogen]] (Factor I, FI) is converted by thrombin to fibrin.  Limited proteolysis of FI results in a fragment named D which when cross-linked by factor XIII is called double-D FIa (DDFIa).  


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