CHEM2052 Tutorial: Difference between revisions
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This arrangement of amino acids is also called a '''charge relay system''' <ref>PMID: 7016210</ref>. | This arrangement of amino acids is also called a '''charge relay system''' <ref>PMID: 7016210</ref>. | ||
Now compare the active site residues of chymotrypsin to the <scene name='59/596400/Morph/2'>trypsin catalytic triad and the elastase catalytic triad</scene>. | Now compare the active site residues of chymotrypsin to the <scene name='59/596400/Morph/2'>trypsin catalytic triad and the elastase catalytic triad</scene> (trypsin is PDB code [[1aq7]] and elastase is PDB code [[4est]]. | ||
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== '''Substrate Binding Pockets''' == | == '''Substrate Binding Pockets''' == | ||
The next links examine the binding pockets of each protein. The spacefilled residues have been color coded according to hydrophobicity (residues are indicated as: {{Template:ColorKey_Hydrophobic}} or {{Template:ColorKey_Polar}}, with <font color="FF0000">'''Aspartate'''</font> highlighted further ). | The next links examine the binding pockets of each protein. The spacefilled residues have been color coded according to hydrophobicity (residues are indicated as: {{Template:ColorKey_Hydrophobic}} or {{Template:ColorKey_Polar}}, with <font color="FF0000">'''Aspartate'''</font> highlighted further ). | ||