Aconitase: Difference between revisions

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== 3D structures of Aconitase==
== 3D structures of Aconitase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|


=== ACO ===
* ACO  


[[1b0k]] – pACO (mutant) – pig<br />
**[[1b0k]] – pACO (mutant) – pig<br />
[[5acn]] – pACO+Fe3S4<br />
**[[5acn]] – pACO+Fe3S4<br />
[[6acn]] - pACO+Fe4S4<br />
**[[6acn]] - pACO+Fe4S4<br />
[[1amj]], [[1nit]] – cACO - cow<br />
**[[1amj]], [[1nit]] – cACO - cow<br />


''ACO+citrate''
*ACO+citrate


[[1c96]] - pACO (mutant)+citrate<br />
**[[1c96]] - pACO (mutant)+citrate<br />
[[1b0m]] - pACO (mutant)+fluorocitrate<br />
**[[1b0m]] - pACO (mutant)+fluorocitrate<br />


''ACO+aconitate''
*ACO+aconitate


[[1fgh]] – cACO+4-hydroxy-aconitate <br />
**[[1fgh]] – cACO+4-hydroxy-aconitate <br />
[[1aco]] – cACO+transaconitate<br />  
**[[1aco]] – cACO+transaconitate<br />  
[[1nis]] - cACO+transaconitate+nitrocitrate<br />
**[[1nis]] - cACO+transaconitate+nitrocitrate<br />


''ACO+isocitrate''
*ACO+isocitrate


[[7acn]] - pACO +isocitrate<br />
**[[7acn]] - pACO +isocitrate<br />
[[1c97]], [[1b0j]] - pACO (mutant)+isocitrate<br />
**[[1c97]], [[1b0j]] - pACO (mutant)+isocitrate<br />
[[1ami]], [[8acn]] – cACO+isocitrate<br />
**[[1ami]], [[8acn]] – cACO+isocitrate<br />


=== ACO1 ===
* ACO1  


[[2b3x]], [[2b3y]] – hACO1 – human<br />
**[2b3x]], [[2b3y]] – hACO1 – human<br />
[[2ipy]], [[3snp]] – rACO1 (mutant)+ferritin H IRE-RNA – rabbit<br />
**[[2ipy]], [[3snp]] – rACO1 (mutant)+ferritin H IRE-RNA – rabbit<br />
[[3sn2]] - rACO1 (mutant)+ transferrin receptor iron regulatory RNA<br />
**[[3sn2]] - rACO1 (mutant)+ transferrin receptor iron regulatory RNA<br />


=== ACO2 ===
* ACO2  
 
[[1l5j]] – ACO2 – ''Escherichia coli''<br />


**[[1l5j]] – ACO2 – ''Escherichia coli''<br />
}}
<!--== Available structures ==
<!--== Available structures ==
In the PDB, nearly all deposited structures are from mammals, [[1l5j]] is from ''E.coli''. Also, only [[2ipy]] shows the IREBP function of cAc---it's also the only from rabbit. There are only two other cAc structures, with and without citrate, also the only from human. All other structures are either cow or pig, and a mutant from pig; all three proteins with several different ligands and inhibitors.
In the PDB, nearly all deposited structures are from mammals, [[1l5j]] is from ''E.coli''. Also, only [[2ipy]] shows the IREBP function of cAc---it's also the only from rabbit. There are only two other cAc structures, with and without citrate, also the only from human. All other structures are either cow or pig, and a mutant from pig; all three proteins with several different ligands and inhibitors.