4uxq: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==FGFR4 in complex with Ponatinib==

~~The entry~~ 4uxq is ~~ON HOLD~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4uxq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXQ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXQ FirstGlance].

~~Authors~~: ~~Tucker~~, J., ~~Klein~~, T., Breed, J., Breeze, A., Overman, R., Phillips, C., ~~Norman, R.A.~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=0LI:3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-{4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}BENZAMIDE'>0LI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </td></tr>

~~Description~~: ~~FGFR4 in complex with Ponatinib~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uxq RCSB], [http://www.ebi.ac.uk/pdbsum/4uxq PDBsum]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Receptor protein-tyrosine kinase]]

[[Category: Breed, J]]

[[Category: Breeze, A]]

[[Category: Klein, T]]

[[Category: Norman, R A]]

[[Category: Overman, R]]

[[Category: Phillips, C]]

[[Category: Tucker, J]]

[[Category: Kinase dfg-out fgfr inhibitor complex]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==FGFR4 in complex with Ponatinib==
+<StructureSection load='4uxq' size='340' side='right' caption='[[4uxq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-The entry 4uxq is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4uxq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXQ FirstGlance]. <br>
-Authors: Tucker, J., Klein, T., Breed, J., Breeze, A., Overman, R., Phillips, C., Norman, R.A.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0LI:3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-{4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}BENZAMIDE'>0LI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
-Description: FGFR4 in complex with Ponatinib
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uxq RCSB], [http://www.ebi.ac.uk/pdbsum/4uxq PDBsum]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: Receptor protein-tyrosine kinase]]
+[[Category: Breed, J]]
+[[Category: Breeze, A]]
+[[Category: Klein, T]]
+[[Category: Norman, R A]]
+[[Category: Overman, R]]
+[[Category: Phillips, C]]
+[[Category: Tucker, J]]
+[[Category: Kinase dfg-out fgfr inhibitor complex]]
+[[Category: Transferase]]