4w9w: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal Structure of BMP-2-inducible kinase in complex with small molecule AZD-7762==

~~The entry~~ 4w9w is ~~ON HOLD~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4w9w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W9W OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W9W FirstGlance].

~~Authors~~: ~~Sorrell~~, F.J., ~~Elkins~~, J.M.~~, Krojer, T~~., ~~Savitsky, P~~.~~, Williams, E~~.~~, Von Delft, F~~., Arrowsmith, C.H., Edwards, A.M., ~~Bountra, C~~., Knapp, S., Structural Genomics Consortium ~~(SGC)~~

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=YDJ:5-(3-FLUOROPHENYL)-N-[(3S)-3-PIPERIDYL]-3-UREIDO-THIOPHENE-2-CARBOXAMIDE'>YDJ</scene>

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </td></tr>

~~Description~~: ~~Crystal Structure of BMP-2~~-~~inducible kinase in complex with small~~ molecule ~~AZD-7762~~

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w9w RCSB], [http://www.ebi.ac.uk/pdbsum/4w9w PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Non-specific serine/threonine protein kinase]]

[[Category: Arrowsmith, C H.]]

[[Category: Bountra, C.]]

[[Category: Delft, F Von.]]

[[Category: Edwards, A M.]]

[[Category: Elkins, J M.]]

[[Category: Knapp, S.]]

[[Category: Krojer, T.]]

[[Category: SGC, Structural Genomics Consortium.]]

[[Category: Savitsky, P.]]

[[Category: Sorrell, F J.]]

[[Category: Williams, E.]]

[[Category: Catalytic domain]]

[[Category: Inhibitor]]

[[Category: Kinase]]

[[Category: Protein binding]]

[[Category: Sgc]]

[[Category: Small-molecule]]

[[Category: Structural genomic]]

[[Category: Structural genomics consortium]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal Structure of BMP-2-inducible kinase in complex with small molecule AZD-7762==
+<StructureSection load='4w9w' size='340' side='right' caption='[[4w9w]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
-The entry 4w9w is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4w9w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W9W FirstGlance]. <br>
-Authors: Sorrell, F.J., Elkins, J.M., Krojer, T., Savitsky, P., Williams, E., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=YDJ:5-(3-FLUOROPHENYL)-N-[(3S)-3-PIPERIDYL]-3-UREIDO-THIOPHENE-2-CARBOXAMIDE'>YDJ</scene><br>
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-Description: Crystal Structure of BMP-2-inducible kinase in complex with small molecule AZD-7762
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w9w RCSB], [http://www.ebi.ac.uk/pdbsum/4w9w PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Arrowsmith, C H.]]
+[[Category: Bountra, C.]]
+[[Category: Delft, F Von.]]
+[[Category: Edwards, A M.]]
+[[Category: Elkins, J M.]]
+[[Category: Knapp, S.]]
+[[Category: Krojer, T.]]
+[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Savitsky, P.]]
+[[Category: Sorrell, F J.]]
+[[Category: Williams, E.]]
+[[Category: Catalytic domain]]
+[[Category: Inhibitor]]
+[[Category: Kinase]]
+[[Category: Protein binding]]
+[[Category: Sgc]]
+[[Category: Small-molecule]]
+[[Category: Structural genomic]]
+[[Category: Structural genomics consortium]]
+[[Category: Transferase]]