1igw: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1igw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGW FirstGlance]. <br>
<table><tr><td colspan='2'>[[1igw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IGW FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aceA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aceA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_lyase Isocitrate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.1 4.1.3.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_lyase Isocitrate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.1 4.1.3.1] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igw RCSB], [http://www.ebi.ac.uk/pdbsum/1igw PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1igw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1igw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1igw RCSB], [http://www.ebi.ac.uk/pdbsum/1igw PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ACEA_ECOLI ACEA_ECOLI]] Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle. May be involved in the assimilation of one-carbon compounds via the isocitrate lyase-positive serine pathway (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Isocitrate lyase]]
[[Category: Isocitrate lyase]]
[[Category: Abeysinghe, I S.B.]]
[[Category: Abeysinghe, I S.B]]
[[Category: Baker, P J.]]
[[Category: Baker, P J]]
[[Category: Barynin, V.]]
[[Category: Barynin, V]]
[[Category: Britton, K L.]]
[[Category: Britton, K L]]
[[Category: Diehl, P.]]
[[Category: Diehl, P]]
[[Category: Langridge, S J.]]
[[Category: Langridge, S J]]
[[Category: McFadden, B A.]]
[[Category: McFadden, B A]]
[[Category: Rice, D W.]]
[[Category: Rice, D W]]
[[Category: Sedelnikova, S E.]]
[[Category: Sedelnikova, S E]]
[[Category: Stillman, T J.]]
[[Category: Stillman, T J]]
[[Category: Weeradechapon, K.]]
[[Category: Weeradechapon, K]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Lyase]]
[[Category: Lyase]]