1nfa: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1nfa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NFA FirstGlance]. <br> | <table><tr><td colspan='2'>[[1nfa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NFA FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NFATC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NFATC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nfa RCSB], [http://www.ebi.ac.uk/pdbsum/1nfa PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nfa RCSB], [http://www.ebi.ac.uk/pdbsum/1nfa PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NFAC1_HUMAN NFAC1_HUMAN]] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chen, L | [[Category: Chen, L]] | ||
[[Category: Crabtree, G R | [[Category: Crabtree, G R]] | ||
[[Category: Dotsch, V | [[Category: Dotsch, V]] | ||
[[Category: Ho, S N | [[Category: Ho, S N]] | ||
[[Category: Verdine, G L | [[Category: Verdine, G L]] | ||
[[Category: Wagner, G | [[Category: Wagner, G]] | ||
[[Category: Wolfe, S A | [[Category: Wolfe, S A]] | ||
[[Category: You, A | [[Category: You, A]] | ||
[[Category: Zhou, P | [[Category: Zhou, P]] | ||
[[Category: Activates cytokine transcription]] | [[Category: Activates cytokine transcription]] | ||
[[Category: Nfat]] | [[Category: Nfat]] | ||
[[Category: Rel-homology fold]] | [[Category: Rel-homology fold]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
