1nrb: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1nrb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Centruroides_sculpturatus Centruroides sculpturatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NRB FirstGlance]. <br> | <table><tr><td colspan='2'>[[1nrb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Centruroides_sculpturatus Centruroides sculpturatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NRB FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nra|1nra]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nra|1nra]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nrb RCSB], [http://www.ebi.ac.uk/pdbsum/1nrb PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nrb RCSB], [http://www.ebi.ac.uk/pdbsum/1nrb PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/SCXV_CENSC SCXV_CENSC]] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Centruroides sculpturatus]] | [[Category: Centruroides sculpturatus]] | ||
[[Category: Jablonsky, M J | [[Category: Jablonsky, M J]] | ||
[[Category: Krishna, N R | [[Category: Krishna, N R]] | ||
[[Category: Neurotoxin]] | [[Category: Neurotoxin]] | ||
