2nm2: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2nm2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NM2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NM2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2nm2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NM2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NM2 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEU:L-NEOPTERIN'>NEU</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEU:L-NEOPTERIN'>NEU</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dhn|1dhn]], [[2dhn|2dhn]], [[1nbu|1nbu]], [[1u68|1u68]], [[1rri|1rri]], [[1rrw|1rrw]], [[1rry|1rry]], [[1rs2|1rs2]], [[1rs4|1rs4]], [[1rsd|1rsd]], [[1rsi|1rsi]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dhn|1dhn]], [[2dhn|2dhn]], [[1nbu|1nbu]], [[1u68|1u68]], [[1rri|1rri]], [[1rrw|1rrw]], [[1rry|1rry]], [[1rs2|1rs2]], [[1rs4|1rs4]], [[1rsd|1rsd]], [[1rsi|1rsi]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroneopterin_aldolase Dihydroneopterin aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.25 4.1.2.25] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroneopterin_aldolase Dihydroneopterin aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.25 4.1.2.25] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nm2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2nm2 RCSB], [http://www.ebi.ac.uk/pdbsum/2nm2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nm2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2nm2 RCSB], [http://www.ebi.ac.uk/pdbsum/2nm2 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/FOLB_STAAU FOLB_STAAU]] Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Dihydroneopterin aldolase]] | [[Category: Dihydroneopterin aldolase]] | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
[[Category: Blaszczyk, J | [[Category: Blaszczyk, J]] | ||
[[Category: Ji, X | [[Category: Ji, X]] | ||
[[Category: Yan, H | [[Category: Yan, H]] | ||
[[Category: 8-dihydroneopterin]] | [[Category: 8-dihydroneopterin]] | ||
[[Category: Dhna]] | [[Category: Dhna]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
