2cu1: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2cu1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CU1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CU1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2cu1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CU1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CU1 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAP3K2, MAPKKK2, MEKK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAP3K2, MAPKKK2, MEKK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cu1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cu1 RCSB], [http://www.ebi.ac.uk/pdbsum/2cu1 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cu1 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cu1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cu1 RCSB], [http://www.ebi.ac.uk/pdbsum/2cu1 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cu1 TOPSAN]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/M3K2_HUMAN M3K2_HUMAN]] Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.<ref>PMID:10713157</ref> <ref>PMID:16001074</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Mitogen-activated protein kinase kinase kinase|Mitogen-activated protein kinase kinase kinase]] | *[[Mitogen-activated protein kinase kinase kinase|Mitogen-activated protein kinase kinase kinase]] | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Hayashi, F | [[Category: Hayashi, F]] | ||
[[Category: Inoue, K | [[Category: Inoue, K]] | ||
[[Category: Nagashima, T | [[Category: Nagashima, T]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Yokoyama, S | [[Category: Yokoyama, S]] | ||
[[Category: Mapk/erk kinase kinase 2]] | [[Category: Mapk/erk kinase kinase 2]] | ||
[[Category: Mek kinase 2]] | [[Category: Mek kinase 2]] | ||
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[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
[[Category: Pb1 domain]] | [[Category: Pb1 domain]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
