2r9o: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2r9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R9O FirstGlance]. <br> | <table><tr><td colspan='2'>[[2r9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R9O FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Y15:N-[(1S)-2-{[(1R)-2-(BENZYLOXY)-1-CYANO-1-METHYLETHYL]AMINO}-1-(CYCLOHEXYLMETHYL)-2-OXOETHYL]MORPHOLINE-4-CARBOXAMIDE'>Y15</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Y15:N-[(1S)-2-{[(1R)-2-(BENZYLOXY)-1-CYANO-1-METHYLETHYL]AMINO}-1-(CYCLOHEXYLMETHYL)-2-OXOETHYL]MORPHOLINE-4-CARBOXAMIDE'>Y15</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r9m|2r9m]], [[2r9n|2r9n]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r9m|2r9m]], [[2r9n|2r9n]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r9o RCSB], [http://www.ebi.ac.uk/pdbsum/2r9o PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r9o RCSB], [http://www.ebi.ac.uk/pdbsum/2r9o PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Cathepsin S]] | [[Category: Cathepsin S]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bekkali, Y | [[Category: Bekkali, Y]] | ||
[[Category: Brown, M L | [[Category: Brown, M L]] | ||
[[Category: Capolino, A | [[Category: Capolino, A]] | ||
[[Category: Crane, K M | [[Category: Crane, K M]] | ||
[[Category: DeTuri, M | [[Category: DeTuri, M]] | ||
[[Category: Emmanuel, M J | [[Category: Emmanuel, M J]] | ||
[[Category: Freeman, D | [[Category: Freeman, D]] | ||
[[Category: Frye, L L | [[Category: Frye, L L]] | ||
[[Category: Girardot, M | [[Category: Girardot, M]] | ||
[[Category: Grygon, C A | [[Category: Grygon, C A]] | ||
[[Category: Hao, M H | [[Category: Hao, M H]] | ||
[[Category: Hrapchak, M | [[Category: Hrapchak, M]] | ||
[[Category: Labadia, M E | [[Category: Labadia, M E]] | ||
[[Category: Liu, W | [[Category: Liu, W]] | ||
[[Category: Morwick, T | [[Category: Morwick, T]] | ||
[[Category: Nelson, R | [[Category: Nelson, R]] | ||
[[Category: Peterson, J D | [[Category: Peterson, J D]] | ||
[[Category: Raymond, E L | [[Category: Raymond, E L]] | ||
[[Category: Spero, D M | [[Category: Spero, D M]] | ||
[[Category: Thomson, D S | [[Category: Thomson, D S]] | ||
[[Category: Wang, Y | [[Category: Wang, Y]] | ||
[[Category: Ward, Y D | [[Category: Ward, Y D]] | ||
[[Category: White, A | [[Category: White, A]] | ||
[[Category: White, D M | [[Category: White, D M]] | ||
[[Category: Wildeson, J | [[Category: Wildeson, J]] | ||
[[Category: Young, E R.R | [[Category: Young, E R.R]] | ||
[[Category: Zindell, R | [[Category: Zindell, R]] | ||
[[Category: Cathepsin]] | [[Category: Cathepsin]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
Revision as of 18:06, 25 December 2014
Cathepsin S complexed with Compound 8
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Cathepsin S
- Homo sapiens
- Bekkali, Y
- Brown, M L
- Capolino, A
- Crane, K M
- DeTuri, M
- Emmanuel, M J
- Freeman, D
- Frye, L L
- Girardot, M
- Grygon, C A
- Hao, M H
- Hrapchak, M
- Labadia, M E
- Liu, W
- Morwick, T
- Nelson, R
- Peterson, J D
- Raymond, E L
- Spero, D M
- Thomson, D S
- Wang, Y
- Ward, Y D
- White, A
- White, D M
- Wildeson, J
- Young, E R.R
- Zindell, R
- Cathepsin
- Glycoprotein
- Hydrolase
- Lysosome
- Protease
- Thiol protease
- Zymogen
