2pq5: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2pq5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PQ5 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2pq5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PQ5 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gwo|2gwo]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gwo|2gwo]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP13, TMDP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP13, TMDP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2pq5 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2pq5 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/DUS13_HUMAN DUS13_HUMAN]] Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.<ref>PMID:21360282</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Barr, A | [[Category: Barr, A]] | ||
[[Category: Berridge, G | [[Category: Berridge, G]] | ||
[[Category: Bunkoczi, G | [[Category: Bunkoczi, G]] | ||
[[Category: Burgess-Brown, N | [[Category: Burgess-Brown, N]] | ||
[[Category: Delft, F von | [[Category: Delft, F von]] | ||
[[Category: Edwards, A | [[Category: Edwards, A]] | ||
[[Category: Knapp, S | [[Category: Knapp, S]] | ||
[[Category: Niesen, F | [[Category: Niesen, F]] | ||
[[Category: Pantic, N | [[Category: Pantic, N]] | ||
[[Category: Pike, A C.W | [[Category: Pike, A C.W]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Salah, E | [[Category: Salah, E]] | ||
[[Category: Savitsky, P | [[Category: Savitsky, P]] | ||
[[Category: Sundstrom, M | [[Category: Sundstrom, M]] | ||
[[Category: Ugochukwu, E | [[Category: Ugochukwu, E]] | ||
[[Category: Uppenberg, J | [[Category: Uppenberg, J]] | ||
[[Category: Weigelt, J | [[Category: Weigelt, J]] | ||
[[Category: Dual specificity phosphatase]] | [[Category: Dual specificity phosphatase]] | ||
[[Category: Dusp13]] | [[Category: Dusp13]] | ||
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[[Category: Protein phosphatase]] | [[Category: Protein phosphatase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Testis and skeletal muscle specific dsp]] | [[Category: Testis and skeletal muscle specific dsp]] | ||
Revision as of 21:51, 24 December 2014
Crystal structure of Dual specificity protein phosphatase 13 (DUSP13)
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Arrowsmith, C H
- Barr, A
- Berridge, G
- Bunkoczi, G
- Burgess-Brown, N
- Delft, F von
- Edwards, A
- Knapp, S
- Niesen, F
- Pantic, N
- Pike, A C.W
- Structural genomic
- Salah, E
- Savitsky, P
- Sundstrom, M
- Ugochukwu, E
- Uppenberg, J
- Weigelt, J
- Dual specificity phosphatase
- Dusp13
- Hydrolase
- Protein phosphatase
- Sgc
- Testis and skeletal muscle specific dsp
