3g2i: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3g2i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G2I FirstGlance]. <br> | <table><tr><td colspan='2'>[[3g2i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G2I FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RUG:1-BETA-D-GLUCOPYRANOSYL-4-(HYDROXYMETHYL)-1H-1,2,3-TRIAZOLE'>RUG</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RUG:1-BETA-D-GLUCOPYRANOSYL-4-(HYDROXYMETHYL)-1H-1,2,3-TRIAZOLE'>RUG</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g2h|3g2h]], [[3g2j|3g2j]], [[3g2k|3g2k]], [[3g2l|3g2l]], [[3g2n|3g2n]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g2h|3g2h]], [[3g2j|3g2j]], [[3g2k|3g2k]], [[3g2l|3g2l]], [[3g2n|3g2n]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g2i RCSB], [http://www.ebi.ac.uk/pdbsum/3g2i PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g2i RCSB], [http://www.ebi.ac.uk/pdbsum/3g2i PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
[[Category: Alexacou, K M | [[Category: Alexacou, K M]] | ||
[[Category: Bokor, E | [[Category: Bokor, E]] | ||
[[Category: Charavgi, M D | [[Category: Charavgi, M D]] | ||
[[Category: Chrysina, E D | [[Category: Chrysina, E D]] | ||
[[Category: Leonidas, D D | [[Category: Leonidas, D D]] | ||
[[Category: Oikonomakos, G N | [[Category: Oikonomakos, G N]] | ||
[[Category: Oikonomakos, N G | [[Category: Oikonomakos, N G]] | ||
[[Category: Somsak, L | [[Category: Somsak, L]] | ||
[[Category: Zographos, S E | [[Category: Zographos, S E]] | ||
[[Category: 3-triazole bioisosterism]] | [[Category: 3-triazole bioisosterism]] | ||
[[Category: Allosteric enzyme]] | [[Category: Allosteric enzyme]] | ||
