1a3q: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1a3q]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A3Q FirstGlance]. <br> | <table><tr><td colspan='2'>[[1a3q]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A3Q FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a3q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a3q RCSB], [http://www.ebi.ac.uk/pdbsum/1a3q PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a3q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a3q RCSB], [http://www.ebi.ac.uk/pdbsum/1a3q PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/NFKB2_HUMAN NFKB2_HUMAN]] Note=A chromosomal aberration involving NFKB2 is found in a case of B-cell non Hodgkin lymphoma (B-NHL). Translocation t(10;14)(q24;q32) with IGHA1. The resulting oncogene is also called Lyt-10C alpha variant. Note=A chromosomal aberration involving NFKB2 is found in a cutaneous T-cell leukemia (C-TCL) cell line. This rearrangement produces the p80HT gene which encodes for a truncated 80 kDa protein (p80HT). Note=In B-cell leukemia (B-CLL) cell line, LB40 and EB308, can be found after heterogeneous chromosomal aberrations, such as internal deletions. | [[http://www.uniprot.org/uniprot/NFKB2_HUMAN NFKB2_HUMAN]] Note=A chromosomal aberration involving NFKB2 is found in a case of B-cell non Hodgkin lymphoma (B-NHL). Translocation t(10;14)(q24;q32) with IGHA1. The resulting oncogene is also called Lyt-10C alpha variant. Note=A chromosomal aberration involving NFKB2 is found in a cutaneous T-cell leukemia (C-TCL) cell line. This rearrangement produces the p80HT gene which encodes for a truncated 80 kDa protein (p80HT). Note=In B-cell leukemia (B-CLL) cell line, LB40 and EB308, can be found after heterogeneous chromosomal aberrations, such as internal deletions. | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Cramer, P | [[Category: Cramer, P]] | ||
[[Category: Larson, C J | [[Category: Larson, C J]] | ||
[[Category: Muller, C W | [[Category: Muller, C W]] | ||
[[Category: Verdine, G L | [[Category: Verdine, G L]] | ||
[[Category: Dna-protein complex]] | [[Category: Dna-protein complex]] | ||
[[Category: Immune response]] | [[Category: Immune response]] | ||
[[Category: Transcription factor]] | [[Category: Transcription factor]] | ||
[[Category: Transcription-dna complex]] | [[Category: Transcription-dna complex]] | ||
