1o8t: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1o8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O8T FirstGlance]. <br>
<table><tr><td colspan='2'>[[1o8t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O8T FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1by6|1by6]], [[1i5j|1i5j]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1by6|1by6]], [[1i5j|1i5j]]</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o8t RCSB], [http://www.ebi.ac.uk/pdbsum/1o8t PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o8t RCSB], [http://www.ebi.ac.uk/pdbsum/1o8t PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/APC2_HUMAN APC2_HUMAN]] Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling.<ref>PMID:9823329</ref> <ref>PMID:10021369</ref> <ref>PMID:11691822</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lycksell, P O.]]
[[Category: Lycksell, P O]]
[[Category: Martinez, G V.]]
[[Category: Martinez, G V]]
[[Category: Nilsson, S.]]
[[Category: Nilsson, S]]
[[Category: Olivecrona, G.]]
[[Category: Olivecrona, G]]
[[Category: Schleucher, J.]]
[[Category: Schleucher, J]]
[[Category: Shen, Y.]]
[[Category: Shen, Y]]
[[Category: Wijmenga, S.]]
[[Category: Wijmenga, S]]
[[Category: Yin, Y.]]
[[Category: Yin, Y]]
[[Category: Zdunek, J.]]
[[Category: Zdunek, J]]
[[Category: Activation mechanism]]
[[Category: Activation mechanism]]
[[Category: Apocii]]
[[Category: Apocii]]