1soa: Difference between revisions
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<StructureSection load='1soa' size='340' side='right' caption='[[1soa]], [[Resolution|resolution]] 1.20Å' scene=''> | <StructureSection load='1soa' size='340' side='right' caption='[[1soa]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1soa]] is a 1 chain structure | <table><tr><td colspan='2'>[[1soa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SOA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SOA FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand= | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p5f|1p5f]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p5f|1p5f]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1soa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1soa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1soa RCSB], [http://www.ebi.ac.uk/pdbsum/1soa PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1soa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1soa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1soa RCSB], [http://www.ebi.ac.uk/pdbsum/1soa PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/PARK7_HUMAN PARK7_HUMAN]] Defects in PARK7 are the cause of Parkinson disease type 7 (PARK7) [MIM:[http://omim.org/entry/606324 606324]]. A neurodegenerative disorder characterized by resting tremor, postural tremor, bradykinesia, muscular rigidity, anxiety and psychotic episodes. PARK7 has onset before 40 years, slow progression and initial good response to levodopa. Some patients may show traits reminiscent of amyotrophic lateral sclerosis-parkinsonism/dementia complex (Guam disease).<ref>PMID:12851414</ref> <ref>PMID:12446870</ref> <ref>PMID:14713311</ref> <ref>PMID:12953260</ref> <ref>PMID:15365989</ref> <ref>PMID:14607841</ref> <ref>PMID:15254937</ref> <ref>PMID:17846173</ref> | [[http://www.uniprot.org/uniprot/PARK7_HUMAN PARK7_HUMAN]] Defects in PARK7 are the cause of Parkinson disease type 7 (PARK7) [MIM:[http://omim.org/entry/606324 606324]]. A neurodegenerative disorder characterized by resting tremor, postural tremor, bradykinesia, muscular rigidity, anxiety and psychotic episodes. PARK7 has onset before 40 years, slow progression and initial good response to levodopa. Some patients may show traits reminiscent of amyotrophic lateral sclerosis-parkinsonism/dementia complex (Guam disease).<ref>PMID:12851414</ref> <ref>PMID:12446870</ref> <ref>PMID:14713311</ref> <ref>PMID:12953260</ref> <ref>PMID:15365989</ref> <ref>PMID:14607841</ref> <ref>PMID:15254937</ref> <ref>PMID:17846173</ref> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Ahmad, R]] | |||
[[Category: Ahmad, R | [[Category: Bandyopadhyay, S]] | ||
[[Category: Bandyopadhyay, S | [[Category: Baptista, M J]] | ||
[[Category: Baptista, M J | [[Category: Canet-Aviles, R]] | ||
[[Category: Canet-Aviles, R | [[Category: Cookson, M R]] | ||
[[Category: Cookson, M R | [[Category: McLendon, C]] | ||
[[Category: McLendon, C | [[Category: Miller, D W]] | ||
[[Category: Miller, D W | [[Category: Petsko, G A]] | ||
[[Category: Petsko, G A | [[Category: Ringe, D]] | ||
[[Category: Ringe, D | [[Category: Wilson, M A]] | ||
[[Category: Wilson, M A | |||
[[Category: Dj-1/thij/pfpi familiy]] | [[Category: Dj-1/thij/pfpi familiy]] | ||
[[Category: Parkinson's disease]] | [[Category: Parkinson's disease]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
