1v7n: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 3: Line 3:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1v7n]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V7N FirstGlance]. <br>
<table><tr><td colspan='2'>[[1v7n]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V7N FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1v7m|1v7m]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1v7m|1v7m]]</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v7n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v7n RCSB], [http://www.ebi.ac.uk/pdbsum/1v7n PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v7n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v7n RCSB], [http://www.ebi.ac.uk/pdbsum/1v7n PDBsum]</span></td></tr>
<table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/TPO_HUMAN TPO_HUMAN]] Defects in THPO are the cause of thrombocythemia type 1 (THCYT1) [MIM:[http://omim.org/entry/187950 187950]]. A myeloproliferative disorder characterized by elevated platelet levels due to sustained proliferation of megakaryocytes, and frequently lead to thrombotic and haemorrhagic complications.<ref>PMID:9425899</ref>   
[[http://www.uniprot.org/uniprot/TPO_HUMAN TPO_HUMAN]] Defects in THPO are the cause of thrombocythemia type 1 (THCYT1) [MIM:[http://omim.org/entry/187950 187950]]. A myeloproliferative disorder characterized by elevated platelet levels due to sustained proliferation of megakaryocytes, and frequently lead to thrombotic and haemorrhagic complications.<ref>PMID:9425899</ref>   
Line 37: Line 37:
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Feese, M D.]]
[[Category: Feese, M D]]
[[Category: Hirose, M.]]
[[Category: Hirose, M]]
[[Category: Kato, T.]]
[[Category: Kato, T]]
[[Category: Kato, Y.]]
[[Category: Kato, Y]]
[[Category: Kuroki, R.]]
[[Category: Kuroki, R]]
[[Category: Maeda, Y.]]
[[Category: Maeda, Y]]
[[Category: Matsukura, Y.]]
[[Category: Matsukura, Y]]
[[Category: Miyazaki, H.]]
[[Category: Miyazaki, H]]
[[Category: Shigematsu, H.]]
[[Category: Shigematsu, H]]
[[Category: Tamada, T.]]
[[Category: Tamada, T]]
[[Category: Fab fragment]]
[[Category: Fab fragment]]
[[Category: Immune system-cytokine complex]]
[[Category: Immune system-cytokine complex]]
[[Category: Thrombopoietin]]
[[Category: Thrombopoietin]]