1x3s: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1x3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X3S FirstGlance]. <br> | <table><tr><td colspan='2'>[[1x3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X3S FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x3s RCSB], [http://www.ebi.ac.uk/pdbsum/1x3s PDBsum], [http://www.topsan.org/Proteins/RSGI/1x3s TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x3s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x3s RCSB], [http://www.ebi.ac.uk/pdbsum/1x3s PDBsum], [http://www.topsan.org/Proteins/RSGI/1x3s TOPSAN]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/RAB18_HUMAN RAB18_HUMAN]] Defects in RAB18 are the cause of Warburg micro syndrome type 3 (WARBM3) [MIM:[http://omim.org/entry/614222 614222]]. WARBM3 is a rare syndrome characterized by microcephaly, microphthalmia, microcornia, congenital cataracts, optic atrophy, cortical dysplasia, in particular corpus callosum hypoplasia, severe mental retardation, spastic diplegia, and hypogonadism.<ref>PMID:21473985</ref> | [[http://www.uniprot.org/uniprot/RAB18_HUMAN RAB18_HUMAN]] Defects in RAB18 are the cause of Warburg micro syndrome type 3 (WARBM3) [MIM:[http://omim.org/entry/614222 614222]]. WARBM3 is a rare syndrome characterized by microcephaly, microphthalmia, microcornia, congenital cataracts, optic atrophy, cortical dysplasia, in particular corpus callosum hypoplasia, severe mental retardation, spastic diplegia, and hypogonadism.<ref>PMID:21473985</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chen, L | [[Category: Chen, L]] | ||
[[Category: Kukimoto-Niino, M | [[Category: Kukimoto-Niino, M]] | ||
[[Category: Liu, Z J | [[Category: Liu, Z J]] | ||
[[Category: Murayama, K | [[Category: Murayama, K]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Shirouzu, M | [[Category: Shirouzu, M]] | ||
[[Category: Wang, B C | [[Category: Wang, B C]] | ||
[[Category: Yokoyama, S | [[Category: Yokoyama, S]] | ||
[[Category: Endocytosis-exocytosis complex]] | [[Category: Endocytosis-exocytosis complex]] | ||
[[Category: Gnp]] | [[Category: Gnp]] | ||
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[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
[[Category: Rab]] | [[Category: Rab]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
Revision as of 12:15, 6 January 2015
Crystal structure of human Rab18 in complex with Gppnhp
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