1t2r: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1t2r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T2R FirstGlance]. <br> | <table><tr><td colspan='2'>[[1t2r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T2R FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t2s|1t2s]], [[1upo|1upo]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t2s|1t2s]], [[1upo|1upo]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t2r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t2r RCSB], [http://www.ebi.ac.uk/pdbsum/1t2r PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t2r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t2r RCSB], [http://www.ebi.ac.uk/pdbsum/1t2r PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/AGO2_DROME AGO2_DROME]] Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger.<ref>PMID:11498593</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Izaurralde, E | [[Category: Izaurralde, E]] | ||
[[Category: Lingel, A | [[Category: Lingel, A]] | ||
[[Category: Sattler, M | [[Category: Sattler, M]] | ||
[[Category: Simon, B | [[Category: Simon, B]] | ||
[[Category: Nucleic acid binding protein]] | [[Category: Nucleic acid binding protein]] | ||
[[Category: Nucleic acid binding protein-rna complex]] | [[Category: Nucleic acid binding protein-rna complex]] | ||
[[Category: Rna]] | [[Category: Rna]] | ||
