1yv6: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1yv6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_pipiens Rana pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YV6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1yv6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_pipiens Rana pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YV6 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yv4|1yv4]], [[1yv7|1yv7]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yv4|1yv4]], [[1yv7|1yv7]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yv6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yv6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yv6 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yv6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yv6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yv6 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/RNP30_RANPI RNP30_RANPI]] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rana pipiens]] | [[Category: Rana pipiens]] | ||
[[Category: Carannante, A | [[Category: Carannante, A]] | ||
[[Category: Donato, A Di | [[Category: Donato, A Di]] | ||
[[Category: Fiore, A Di | [[Category: Fiore, A Di]] | ||
[[Category: Mazzarella, L | [[Category: Mazzarella, L]] | ||
[[Category: Merlino, A | [[Category: Merlino, A]] | ||
[[Category: Notomista, E | [[Category: Notomista, E]] | ||
[[Category: Sica, F | [[Category: Sica, F]] | ||
[[Category: Antitumor action]] | [[Category: Antitumor action]] | ||
[[Category: Dynamic]] | [[Category: Dynamic]] | ||
Revision as of 21:16, 24 December 2014
X-ray structure of M23L onconase at 298K
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