2dkz: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2dkz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2dkz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKZ FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">COL07333 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">COL07333 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dkz RCSB], [http://www.ebi.ac.uk/pdbsum/2dkz PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkz TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dkz RCSB], [http://www.ebi.ac.uk/pdbsum/2dkz PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkz TOPSAN]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/FA59A_HUMAN FA59A_HUMAN]] Isoform 1: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Goroncy, A K.]]
[[Category: Goroncy, A K]]
[[Category: Inoue, M.]]
[[Category: Inoue, M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa, T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba, S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Structural genomic]]
[[Category: Sato, M.]]
[[Category: Sato, M]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama, S]]
[[Category: Cell-free protein synthesis]]
[[Category: Cell-free protein synthesis]]
[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
[[Category: Protein regulation]]
[[Category: Protein regulation]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Rsgi]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
[[Category: Structural genomic]]