2ck2: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ck2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CK2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CK2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ck2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CK2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CK2 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e88|1e88]], [[1e8b|1e8b]], [[1fbr|1fbr]], [[1fna|1fna]], [[1fnf|1fnf]], [[1fnh|1fnh]], [[1j8k|1j8k]], [[1o9a|1o9a]], [[1oww|1oww]], [[1q38|1q38]], [[1qgb|1qgb]], [[1qo6|1qo6]], [[1ttf|1ttf]], [[1ttg|1ttg]], [[2cg6|2cg6]], [[2cg7|2cg7]], [[2fn2|2fn2]], [[2fnb|2fnb]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e88|1e88]], [[1e8b|1e8b]], [[1fbr|1fbr]], [[1fna|1fna]], [[1fnf|1fnf]], [[1fnh|1fnh]], [[1j8k|1j8k]], [[1o9a|1o9a]], [[1oww|1oww]], [[1q38|1q38]], [[1qgb|1qgb]], [[1qo6|1qo6]], [[1ttf|1ttf]], [[1ttg|1ttg]], [[2cg6|2cg6]], [[2cg7|2cg7]], [[2fn2|2fn2]], [[2fnb|2fnb]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ck2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ck2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ck2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ck2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ck2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ck2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ck2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ck2 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/FINC_HUMAN FINC_HUMAN]] Defects in FN1 are the cause of glomerulopathy with fibronectin deposits type 2 (GFND2) [MIM:[http://omim.org/entry/601894 601894]]; also known as familial glomerular nephritis with fibronectin deposits or fibronectin glomerulopathy. GFND is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life.<ref>PMID:18268355</ref> | [[http://www.uniprot.org/uniprot/FINC_HUMAN FINC_HUMAN]] Defects in FN1 are the cause of glomerulopathy with fibronectin deposits type 2 (GFND2) [MIM:[http://omim.org/entry/601894 601894]]; also known as familial glomerular nephritis with fibronectin deposits or fibronectin glomerulopathy. GFND is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life.<ref>PMID:18268355</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Allen, M D | [[Category: Allen, M D]] | ||
[[Category: Best, R B | [[Category: Best, R B]] | ||
[[Category: Billings, K S | [[Category: Billings, K S]] | ||
[[Category: Clarke, J | [[Category: Clarke, J]] | ||
[[Category: Erickson, H P | [[Category: Erickson, H P]] | ||
[[Category: Ng, S P | [[Category: Ng, S P]] | ||
[[Category: Ohashi, T | [[Category: Ohashi, T]] | ||
[[Category: Randles, L G | [[Category: Randles, L G]] | ||
[[Category: Acute phase]] | [[Category: Acute phase]] | ||
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
