2kr5: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kr5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_parasiticus Aspergillus parasiticus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KR5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kr5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_parasiticus Aspergillus parasiticus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KR5 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pksL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5067 Aspergillus parasiticus])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pksL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5067 Aspergillus parasiticus])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kr5 RCSB], [http://www.ebi.ac.uk/pdbsum/2kr5 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kr5 RCSB], [http://www.ebi.ac.uk/pdbsum/2kr5 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PKSL1_ASPPA PKSL1_ASPPA]] Combines a hexanoyl starter unit and 7 malonyl-CoA extender units to synthesize the precursor norsolorinic acid anthrone (noranthrone) in the aflatoxin biosynthesis pathway. The hexanoyl starter unit is provided to the acyl-carrier protein (ACP) domain by a dedicated fungal fatty acid synthase.<ref>PMID:15006741</ref> <ref>PMID:18403714</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Aspergillus parasiticus]]
[[Category: Aspergillus parasiticus]]
[[Category: Cox, R J.]]
[[Category: Cox, R J]]
[[Category: Crosby, J.]]
[[Category: Crosby, J]]
[[Category: Crump, M P.]]
[[Category: Crump, M P]]
[[Category: Ploskon, E.]]
[[Category: Ploskon, E]]
[[Category: Simpson, T J.]]
[[Category: Simpson, T J]]
[[Category: Wattana-amorn, P.]]
[[Category: Wattana-amorn, P]]
[[Category: Williams, C.]]
[[Category: Williams, C]]
[[Category: Acyl carrrier protein]]
[[Category: Acyl carrrier protein]]
[[Category: Aflatoxin biosynthesis]]
[[Category: Aflatoxin biosynthesis]]