2k4u: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2k4u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K4U FirstGlance]. <br> | <table><tr><td colspan='2'>[[2k4u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K4U FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k4u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k4u RCSB], [http://www.ebi.ac.uk/pdbsum/2k4u PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k4u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k4u RCSB], [http://www.ebi.ac.uk/pdbsum/2k4u PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/KAX36_MESMA KAX36_MESMA]] Blocks voltage-gated potassium channels. At 2 uM, blocks rat Kv1.1/KCNA1 and Kv1.3/KCNA3, has a strong effect on rat Kv1.2/KCNA2 and Kv1.6/KCNA6 as well as a moderate effect on Shaker IR.<ref>PMID:9354615</ref> <ref>PMID:20713119</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mesobuthus martensii]] | [[Category: Mesobuthus martensii]] | ||
[[Category: Cao, Z J | [[Category: Cao, Z J]] | ||
[[Category: Han, S | [[Category: Han, S]] | ||
[[Category: Jiang, L | [[Category: Jiang, L]] | ||
[[Category: Li, W X | [[Category: Li, W X]] | ||
[[Category: Liu, H | [[Category: Liu, H]] | ||
[[Category: Liu, M L | [[Category: Liu, M L]] | ||
[[Category: Wu, Y L | [[Category: Wu, Y L]] | ||
[[Category: Yang, D W | [[Category: Yang, D W]] | ||
[[Category: Yi, H | [[Category: Yi, H]] | ||
[[Category: Yin, S J | [[Category: Yin, S J]] | ||
[[Category: Adwx-1 peptide selectivity]] | [[Category: Adwx-1 peptide selectivity]] | ||
[[Category: Amidation]] | [[Category: Amidation]] | ||
Revision as of 09:47, 25 December 2014
Solution structure of the SCORPION TOXIN ADWX-1
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