2gzv: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2gzv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GZV FirstGlance]. <br> | <table><tr><td colspan='2'>[[2gzv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GZV FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PICK1, PRKCABP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PICK1, PRKCABP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gzv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gzv RCSB], [http://www.ebi.ac.uk/pdbsum/2gzv PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gzv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gzv RCSB], [http://www.ebi.ac.uk/pdbsum/2gzv PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PICK1_HUMAN PICK1_HUMAN]] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ASIC1/ASIC3 channel.<ref>PMID:20403402</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C | [[Category: Arrowsmith, C]] | ||
[[Category: Berridge, G | [[Category: Berridge, G]] | ||
[[Category: Bray, J | [[Category: Bray, J]] | ||
[[Category: Colebrook, S | [[Category: Colebrook, S]] | ||
[[Category: Debreczeni, J E | [[Category: Debreczeni, J E]] | ||
[[Category: Delft, F von | [[Category: Delft, F von]] | ||
[[Category: Doyle, D A | [[Category: Doyle, D A]] | ||
[[Category: Edwards, A | [[Category: Edwards, A]] | ||
[[Category: Elkins, J M | [[Category: Elkins, J M]] | ||
[[Category: Gileadi, O | [[Category: Gileadi, O]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Savitsky, P | [[Category: Savitsky, P]] | ||
[[Category: Smee, C | [[Category: Smee, C]] | ||
[[Category: Sundstrom, M | [[Category: Sundstrom, M]] | ||
[[Category: Turnbull, A | [[Category: Turnbull, A]] | ||
[[Category: Weigelt, J | [[Category: Weigelt, J]] | ||
[[Category: Yang, X | [[Category: Yang, X]] | ||
[[Category: Pdz domain]] | [[Category: Pdz domain]] | ||
[[Category: Protein kinase c]] | [[Category: Protein kinase c]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
