2js7: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2js7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JS7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JS7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2js7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JS7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JS7 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYD88 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYD88 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2js7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2js7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2js7 RCSB], [http://www.ebi.ac.uk/pdbsum/2js7 PDBsum], [http://www.topsan.org/Proteins/NESGC/2js7 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2js7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2js7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2js7 RCSB], [http://www.ebi.ac.uk/pdbsum/2js7 PDBsum], [http://www.topsan.org/Proteins/NESGC/2js7 TOPSAN]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/MYD88_HUMAN MYD88_HUMAN]] Defects in MYD88 are the cause of MYD88 deficiency (MYD88D) [MIM:[http://omim.org/entry/612260 612260]]; also known as recurrent pyogenic bacterial infections due to MYD88 deficiency. Patients suffer from autosomal recessive, life-threatening, often recurrent pyogenic bacterial infections, including invasive pneumococcal disease, and die between 1 and 11 months of age. Surviving patients are otherwise healthy, with normal resistance to other microbes, and their clinical status improved with age.<ref>PMID:19506249</ref> <ref>PMID:18669862</ref> | [[http://www.uniprot.org/uniprot/MYD88_HUMAN MYD88_HUMAN]] Defects in MYD88 are the cause of MYD88 deficiency (MYD88D) [MIM:[http://omim.org/entry/612260 612260]]; also known as recurrent pyogenic bacterial infections due to MYD88 deficiency. Patients suffer from autosomal recessive, life-threatening, often recurrent pyogenic bacterial infections, including invasive pneumococcal disease, and die between 1 and 11 months of age. Surviving patients are otherwise healthy, with normal resistance to other microbes, and their clinical status improved with age.<ref>PMID:19506249</ref> <ref>PMID:18669862</ref> | ||
| Line 25: | Line 25: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acton, T B | [[Category: Acton, T B]] | ||
[[Category: Ciano, M | [[Category: Ciano, M]] | ||
[[Category: Ho, C | [[Category: Ho, C]] | ||
[[Category: Kennedy, M A | [[Category: Kennedy, M A]] | ||
[[Category: Ma, L-C | [[Category: Ma, L-C]] | ||
[[Category: Montelione, G T | [[Category: Montelione, G T]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Ramelot, T A | [[Category: Ramelot, T A]] | ||
[[Category: Rossi, P | [[Category: Rossi, P]] | ||
[[Category: Tao, X | [[Category: Tao, X]] | ||
[[Category: Tong, L | [[Category: Tong, L]] | ||
[[Category: Xiao, R | [[Category: Xiao, R]] | ||
[[Category: Innate immune signaling]] | [[Category: Innate immune signaling]] | ||
[[Category: Myd88_human]] | [[Category: Myd88_human]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
[[Category: | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Tir domain]] | [[Category: Tir domain]] | ||
[[Category: Toll like receptor adaptor domain]] | [[Category: Toll like receptor adaptor domain]] | ||
