2vt0: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vt0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VT0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VT0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vt0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VT0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VT0 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBU:(1R,2R,3S,4S,5S,6S)-CYCLOHEXANE-1,2,3,4,5,6-HEXOL'>CBU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBU:(1R,2R,3S,4S,5S,6S)-CYCLOHEXANE-1,2,3,4,5,6-HEXOL'>CBU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosylceramidase Glucosylceramidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosylceramidase Glucosylceramidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vt0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vt0 RCSB], [http://www.ebi.ac.uk/pdbsum/2vt0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vt0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vt0 RCSB], [http://www.ebi.ac.uk/pdbsum/2vt0 PDBsum]</span></td></tr>
<table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Glucosylceramidase]]
[[Category: Glucosylceramidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Aviezer, D.]]
[[Category: Aviezer, D]]
[[Category: Brumshtein, B.]]
[[Category: Brumshtein, B]]
[[Category: Futerman, A H.]]
[[Category: Futerman, A H]]
[[Category: Greenblatt, H M.]]
[[Category: Greenblatt, H M]]
[[Category: Shaaltiel, Y.]]
[[Category: Shaaltiel, Y]]
[[Category: Silman, I.]]
[[Category: Silman, I]]
[[Category: Sussman, J L.]]
[[Category: Sussman, J L]]
[[Category: Alternative initiation]]
[[Category: Alternative initiation]]
[[Category: Cerezyme]]
[[Category: Cerezyme]]
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[[Category: Glycosidase]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: ISPC]]
[[Category: ISPC, Israel Structural Proteomics Center]]
[[Category: Israel Structural Proteomics Center]]
[[Category: Lipid metabolism]]
[[Category: Lipid metabolism]]
[[Category: Lysosome]]
[[Category: Lysosome]]