2vaq: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vaq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAQ FirstGlance]. <br> | <table><tr><td colspan='2'>[[2vaq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAQ FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VAW:(2S,3R,4S)-METHYL+4-(2-(2-(1H-INDOL-3-YL)ETHYLAMINO)ETHYL)-2-((2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-YLOXY)-3-VINYL-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE'>VAW</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VAW:(2S,3R,4S)-METHYL+4-(2-(2-(1H-INDOL-3-YL)ETHYLAMINO)ETHYL)-2-((2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-YLOXY)-3-VINYL-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE'>VAW</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fp8|2fp8]], [[2fp9|2fp9]], [[2fpb|2fpb]], [[2v91|2v91]], [[2fpc|2fpc]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fp8|2fp8]], [[2fp9|2fp9]], [[2fpb|2fpb]], [[2v91|2v91]], [[2fpc|2fpc]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Strictosidine_synthase Strictosidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.2 4.3.3.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Strictosidine_synthase Strictosidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.2 4.3.3.2] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vaq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vaq RCSB], [http://www.ebi.ac.uk/pdbsum/2vaq PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vaq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vaq RCSB], [http://www.ebi.ac.uk/pdbsum/2vaq PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/STSY_RAUSE STSY_RAUSE]] Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 35: | Line 37: | ||
[[Category: Rauvolfia serpentina]] | [[Category: Rauvolfia serpentina]] | ||
[[Category: Strictosidine synthase]] | [[Category: Strictosidine synthase]] | ||
[[Category: Friedrich, A | [[Category: Friedrich, A]] | ||
[[Category: Giddings, L A | [[Category: Giddings, L A]] | ||
[[Category: Loris, E A | [[Category: Loris, E A]] | ||
[[Category: Maresh, J | [[Category: Maresh, J]] | ||
[[Category: Oconnor, S E | [[Category: Oconnor, S E]] | ||
[[Category: Panjikar, S | [[Category: Panjikar, S]] | ||
[[Category: Peters, B | [[Category: Peters, B]] | ||
[[Category: Stoeckigt, J | [[Category: Stoeckigt, J]] | ||
[[Category: Trout, B L | [[Category: Trout, B L]] | ||
[[Category: Alkaloid metabolism]] | [[Category: Alkaloid metabolism]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
