2vde: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vde]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VDE FirstGlance]. <br> | <table><tr><td colspan='2'>[[2vde]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VDE FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tqq|1tqq]], [[1ttq|1ttq]], [[1ek9|1ek9]], [[2vdd|2vdd]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tqq|1tqq]], [[1ttq|1ttq]], [[1ek9|1ek9]], [[2vdd|2vdd]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vde RCSB], [http://www.ebi.ac.uk/pdbsum/2vde PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vde RCSB], [http://www.ebi.ac.uk/pdbsum/2vde PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TOLC_ECOLI TOLC_ECOLI]] Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells.<ref>PMID:6337123</ref> <ref>PMID:11274125</ref> <ref>PMID:15228545</ref> <ref>PMID:18955484</ref> <ref>PMID:23176499</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Bavro, V N | [[Category: Bavro, V N]] | ||
[[Category: Fernandez-Recio, J | [[Category: Fernandez-Recio, J]] | ||
[[Category: Furnham, N | [[Category: Furnham, N]] | ||
[[Category: Luisi, B | [[Category: Luisi, B]] | ||
[[Category: Misra, R | [[Category: Misra, R]] | ||
[[Category: Pei, X Y | [[Category: Pei, X Y]] | ||
[[Category: Perez-Cano, L | [[Category: Perez-Cano, L]] | ||
[[Category: Pietras, Z | [[Category: Pietras, Z]] | ||
[[Category: Truer, R | [[Category: Truer, R]] | ||
[[Category: Alpha helical barrel]] | [[Category: Alpha helical barrel]] | ||
[[Category: Beta barrel]] | [[Category: Beta barrel]] | ||
