3a2k: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3a2k]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_kaustophilus Geobacillus kaustophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2K FirstGlance]. <br>
<table><tr><td colspan='2'>[[3a2k]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_kaustophilus Geobacillus kaustophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2K FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GK0060, tilS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1462 Geobacillus kaustophilus])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GK0060, tilS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1462 Geobacillus kaustophilus])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a2k RCSB], [http://www.ebi.ac.uk/pdbsum/3a2k PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a2k RCSB], [http://www.ebi.ac.uk/pdbsum/3a2k PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TILS_GEOKA TILS_GEOKA]] Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Geobacillus kaustophilus]]
[[Category: Geobacillus kaustophilus]]
[[Category: Bonnefond, L.]]
[[Category: Bonnefond, L]]
[[Category: Ishitani, R.]]
[[Category: Ishitani, R]]
[[Category: Nakanishi, K.]]
[[Category: Nakanishi, K]]
[[Category: Nureki, O.]]
[[Category: Nureki, O]]
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Ligase-rna complex]]
[[Category: Ligase-rna complex]]
[[Category: Pseudo-knot]]
[[Category: Pseudo-knot]]
[[Category: Rna]]
[[Category: Rna]]