2wqb: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wqb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WQB FirstGlance]. <br> | <table><tr><td colspan='2'>[[2wqb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WQB FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QQ1:2-[3-(CYCLOHEXYLMETHYL)-5-PHENYL-IMIDAZOL-4-YL]-[1,3]THIAZOLO[4,5-E]PYRIMIDIN-7-AMINE'>QQ1</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QQ1:2-[3-(CYCLOHEXYLMETHYL)-5-PHENYL-IMIDAZOL-4-YL]-[1,3]THIAZOLO[4,5-E]PYRIMIDIN-7-AMINE'>QQ1</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gy5|2gy5]], [[1fvr|1fvr]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gy5|2gy5]], [[1fvr|1fvr]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wqb RCSB], [http://www.ebi.ac.uk/pdbsum/2wqb PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wqb RCSB], [http://www.ebi.ac.uk/pdbsum/2wqb PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Brassington, C | [[Category: Brassington, C]] | ||
[[Category: Breed, J | [[Category: Breed, J]] | ||
[[Category: Buttar, D | [[Category: Buttar, D]] | ||
[[Category: Fitzek, M | [[Category: Fitzek, M]] | ||
[[Category: Forder, C | [[Category: Forder, C]] | ||
[[Category: Hassall, L | [[Category: Hassall, L]] | ||
[[Category: Hayter, B R | [[Category: Hayter, B R]] | ||
[[Category: Jones, C D | [[Category: Jones, C D]] | ||
[[Category: Luke, R W.A | [[Category: Luke, R W.A]] | ||
[[Category: McCall, E | [[Category: McCall, E]] | ||
[[Category: McCoull, W | [[Category: McCoull, W]] | ||
[[Category: McMiken, H | [[Category: McMiken, H]] | ||
[[Category: Norman, R | [[Category: Norman, R]] | ||
[[Category: Paterson, D | [[Category: Paterson, D]] | ||
[[Category: Rowsell, S | [[Category: Rowsell, S]] | ||
[[Category: Tucker, J A | [[Category: Tucker, J A]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
Revision as of 11:21, 20 January 2015
Structure of the Tie2 kinase domain in complex with a thiazolopyrimidine inhibitor
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Receptor protein-tyrosine kinase
- Brassington, C
- Breed, J
- Buttar, D
- Fitzek, M
- Forder, C
- Hassall, L
- Hayter, B R
- Jones, C D
- Luke, R W.A
- McCall, E
- McCoull, W
- McMiken, H
- Norman, R
- Paterson, D
- Rowsell, S
- Tucker, J A
- Atp-binding
- Disease mutation
- Glycoprotein
- Kinase
- Nucleotide-binding
- Oncology
- Phosphoprotein
- Phosphotransferase
- Receptor
- Thiazolopyrimidine
- Transferase
- Tyrosine-protein kinase
