2ch8: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ch8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_4 Human herpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CH8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CH8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ch8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_4 Human herpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CH8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CH8 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ch8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ch8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ch8 RCSB], [http://www.ebi.ac.uk/pdbsum/2ch8 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ch8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ch8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ch8 RCSB], [http://www.ebi.ac.uk/pdbsum/2ch8 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/BRF1_EBV BRF1_EBV]] Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.<ref>PMID:15064715</ref> <ref>PMID:15778977</ref> <ref>PMID:16054293</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human herpesvirus 4]] | [[Category: Human herpesvirus 4]] | ||
[[Category: Burmeister, W P | [[Category: Burmeister, W P]] | ||
[[Category: Deturenne-Tessier, M | [[Category: Deturenne-Tessier, M]] | ||
[[Category: Ooka, T | [[Category: Ooka, T]] | ||
[[Category: Ruggiero, F | [[Category: Ruggiero, F]] | ||
[[Category: Tarbouriech, N | [[Category: Tarbouriech, N]] | ||
[[Category: Barf1]] | [[Category: Barf1]] | ||
[[Category: Early protein]] | [[Category: Early protein]] | ||
