4ogp: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ogp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ogp RCSB], [http://www.ebi.ac.uk/pdbsum/4ogp PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ogp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ogp RCSB], [http://www.ebi.ac.uk/pdbsum/4ogp PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PAT1_YEAST PAT1_YEAST]] Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation. First decay factor recruited to mRNA, at a time when the mRNA is still associated with translation factors. Subsequently, PAT1 recruits the hepta-heterodimer LSM1-LSM7 complex to P-bodies. In association with the LSM1-LSM7 complex, stabilizes the 3' terminus of mRNAs. This association is also required for mosaic virus genomic RNA translation. Modulates the rates of mRNA-decapping that occur following deadenylation. Might be required for promoting the formation or the stabilization of the preinitiation translation complexes. Required for 40S ribosomal subunit joining to capped and/or polyadenylated mRNA. With other P-body components, enhances the formation of retrotransposition-competent Ty1 virus-like particles. Necessary for accurate chromosome transmission during cell division.<ref>PMID:8816497</ref> <ref>PMID:8972867</ref> <ref>PMID:10523645</ref> <ref>PMID:10394921</ref> <ref>PMID:10747033</ref> <ref>PMID:10779343</ref> <ref>PMID:10913177</ref> <ref>PMID:11027264</ref> <ref>PMID:10761922</ref> <ref>PMID:11514438</ref> <ref>PMID:12773554</ref> <ref>PMID:16179257</ref> <ref>PMID:17875743</ref> <ref>PMID:17429074</ref> <ref>PMID:17513695</ref> <ref>PMID:18086885</ref> <ref>PMID:19901074</ref> <ref>PMID:20832728</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Back, R | [[Category: Back, R]] | ||
[[Category: Fourati-Kammoun, Z | [[Category: Fourati-Kammoun, Z]] | ||
[[Category: Gaudon-Plesse, C | [[Category: Gaudon-Plesse, C]] | ||
[[Category: Graille, M | [[Category: Graille, M]] | ||
[[Category: Keller, J | [[Category: Keller, J]] | ||
[[Category: Kolesnikova, O | [[Category: Kolesnikova, O]] | ||
[[Category: Lazar, N | [[Category: Lazar, N]] | ||
[[Category: Seraphin, B | [[Category: Seraphin, B]] | ||
[[Category: Arm-repeat fold]] | [[Category: Arm-repeat fold]] | ||
[[Category: Dcp2]] | [[Category: Dcp2]] | ||
[[Category: Lsm1-7]] | [[Category: Lsm1-7]] | ||
[[Category: Rna binding protein]] | [[Category: Rna binding protein]] | ||
