2qzd: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qzd RCSB], [http://www.ebi.ac.uk/pdbsum/2qzd PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qzd RCSB], [http://www.ebi.ac.uk/pdbsum/2qzd PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bowman, V D | [[Category: Bowman, V D]] | ||
[[Category: Chipman, P R | [[Category: Chipman, P R]] | ||
[[Category: Hafenstein, S | [[Category: Hafenstein, S]] | ||
[[Category: Kelly, C M.Bator | [[Category: Kelly, C M.Bator]] | ||
[[Category: Lin, F | [[Category: Lin, F]] | ||
[[Category: Medof, M E | [[Category: Medof, M E]] | ||
[[Category: Rossmann, M G | [[Category: Rossmann, M G]] | ||
[[Category: Blood group antigen]] | [[Category: Blood group antigen]] | ||
[[Category: Complement pathway]] | [[Category: Complement pathway]] | ||
