Sigma factor: Difference between revisions
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<StructureSection load='1rio' size='340' side='right' caption='Structure of sigma factor region 4 (red) complex with DNA, repression protein CI (grey and green), MPD and Ca+2 (green) (PDB code [[1rio]]).' scene=''> | <StructureSection load='1rio' size='340' side='right' caption='Structure of sigma factor region 4 (red) complex with DNA, repression protein CI (grey and green), MPD and Ca+2 (green) (PDB code [[1rio]]).' scene=''> | ||
== Function == | == Structure & Function == | ||
'''Sigma (σ) factor''' is needed for the initiation of RNA transcription. The large and biologically essential protein, RNA polymerase (RNAP), contains one σ-subunit, which binds <scene name='59/591940/Dna_promoter/1'>Promoter Sequences</scene>, located upstream of transcription start sites. | '''Sigma (σ) factor''' is needed for the initiation of RNA transcription. The large and biologically essential protein, RNA polymerase (RNAP), contains one σ-subunit, which binds <scene name='59/591940/Dna_promoter/1'>Promoter Sequences</scene>, located upstream of transcription start sites. | ||
== Disease == | == Disease == | ||
