Sigma factor: Difference between revisions

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<StructureSection load='1rio' size='340' side='right' caption='Structure of sigma factor region 4 (red) complex with DNA, repression protein CI (grey and green), MPD and Ca+2 (green) (PDB code [[1rio]]).' scene=''>
<StructureSection load='1rio' size='340' side='right' caption='Structure of sigma factor region 4 (red) complex with DNA, repression protein CI (grey and green), MPD and Ca+2 (green) (PDB code [[1rio]]).' scene=''>


== Structure & Function ==
== Overview ==


'''Sigma (σ) factor''' is the peoptide subunite needed for the initiation of RNA transcription in prokaryotic organisms.  As opposed to eukaryotes, who utilize a variety of proteins to initiate gene transcription, prokaryotes only use the σ-factor.  The large and biologically essential protein, RNA polymerase (RNAP), contains one σ-subunit, which binds <scene name='59/591940/Dna_promoter/1'>Promoter Sequences</scene>, located upstream of transcription start sites.   
'''Sigma (σ) factor''' is the peoptide subunit needed for the initiation of RNA transcription in prokaryotic organisms.  As opposed to eukaryotes, who utilize a variety of proteins to initiate gene transcription, prokaryotes only use the σ-factor.  The large and biologically essential protein, RNA polymerase (RNAP), contains one σ-subunit, which binds <scene name='59/591940/Dna_promoter/1'>Promoter Sequences</scene>, located upstream of transcription start sites.   


== Disease ==
== Specific Function and Structure ==


== Relevance ==
== Relevance ==