2k3u: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k3u RCSB], [http://www.ebi.ac.uk/pdbsum/2k3u PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k3u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k3u RCSB], [http://www.ebi.ac.uk/pdbsum/2k3u PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CHIPS_STAAE CHIPS_STAAE]] Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium.<ref>PMID:14993252</ref> <ref>PMID:15153520</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Staphylococcus aureus subsp. aureus str. newman]] | [[Category: Staphylococcus aureus subsp. aureus str. newman]] | ||
[[Category: Bunschoten, A | [[Category: Bunschoten, A]] | ||
[[Category: Ippel, J H | [[Category: Ippel, J H]] | ||
[[Category: Kemmink, J | [[Category: Kemmink, J]] | ||
[[Category: Liskamp, R | [[Category: Liskamp, R]] | ||
[[Category: Anaphylotoxin c5a]] | [[Category: Anaphylotoxin c5a]] | ||
[[Category: Complement cascade]] | [[Category: Complement cascade]] | ||
