4k6l: Difference between revisions
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<StructureSection load='4k6l' size='340' side='right' caption='[[4k6l]], [[Resolution|resolution]] 2.39Å' scene=''> | <StructureSection load='4k6l' size='340' side='right' caption='[[4k6l]], [[Resolution|resolution]] 2.39Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4k6l]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6L FirstGlance]. <br> | <table><tr><td colspan='2'>[[4k6l]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhi"_schroeter_1886 "bacillus typhi" schroeter 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6L FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STY1891, t1107 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886]), cdtB, STY1886, t1111 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886]), STY1890, t1108 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6l RCSB], [http://www.ebi.ac.uk/pdbsum/4k6l PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6l RCSB], [http://www.ebi.ac.uk/pdbsum/4k6l PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CDTB_SALTI CDTB_SALTI]] Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Galan, J | [[Category: Bacillus typhi schroeter 1886]] | ||
[[Category: Gao, X | [[Category: Galan, J]] | ||
[[Category: Song, J | [[Category: Gao, X]] | ||
[[Category: Song, J]] | |||
[[Category: Bacterial toxin]] | [[Category: Bacterial toxin]] | ||
[[Category: Complex]] | [[Category: Complex]] | ||
[[Category: Sugar]] | [[Category: Sugar]] | ||
[[Category: Toxin]] | [[Category: Toxin]] | ||
