Rossmann fold: Difference between revisions
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To illustrate a βαβ fold in a complete protein, a 3D example (PDB ID: [[1f3p]]) is shown below. The example protein is a ferredoxin reductase from Pseudomonas that binds both an FAD and NADH <ref>PMID:11090282</ref>. This enzyme binds NADH which transfers its two electrons to the FAD coenzyme of ferredoxin reductase. These electrons are then transferred to a ferredoxin that is an iron sulfur electron transfer protein. This ferredoxin then donates the electrons to an oxygenase that uses the electrons in a dioxygenase reaction. | To illustrate a βαβ fold in a complete protein, a 3D example (PDB ID: [[1f3p]]) is shown below. The example protein is a ferredoxin reductase from Pseudomonas that binds both an FAD and NADH <ref>PMID:11090282</ref>. This enzyme binds NADH which transfers its two electrons to the FAD coenzyme of ferredoxin reductase. These electrons are then transferred to a ferredoxin that is an iron sulfur electron transfer protein. This ferredoxin then donates the electrons to an oxygenase that uses the electrons in a dioxygenase reaction. | ||
Below the two core β-strands of the FAD binding site of the enzyme (PDB ID: | Below the two core β-strands of the FAD binding site of the enzyme (PDB ID: [[1f3p]]) are shown in cyan colored "rocket" format, with a red colored helix in between the two strands. | ||
<Structure load='1f3p' size='500' frame='true' align='left' caption='Fig. 4. FAD binding site of ferredoxin reductase. PDB ID: | <Structure load='1f3p' size='500' frame='true' align='left' caption='Fig. 4. FAD binding site of ferredoxin reductase. PDB ID: [[1f3p]].' scene='59/595757/Ferredoxin-reductase-fad/2' /> | ||
The following scenes illustrate some aspects of the structure. | The following scenes illustrate some aspects of the structure. | ||
