2q3o: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q3o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q3o RCSB], [http://www.ebi.ac.uk/pdbsum/2q3o PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q3o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q3o RCSB], [http://www.ebi.ac.uk/pdbsum/2q3o PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/OPR3_ARATH OPR3_ARATH]] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. Required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program. In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).<ref>PMID:10973494</ref> <ref>PMID:19605548</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: 12-oxophytodienoate reductase]] | [[Category: 12-oxophytodienoate reductase]] | ||
[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Kondrashov, D A | [[Category: Kondrashov, D A]] | ||
[[Category: Levin, E J | [[Category: Levin, E J]] | ||
[[Category: Phillips, G N | [[Category: Phillips, G N]] | ||
[[Category: Wesenberg, G E | [[Category: Wesenberg, G E]] | ||
[[Category: Cesg]] | [[Category: Cesg]] | ||
[[Category: Ensemble refinement]] | [[Category: Ensemble refinement]] | ||
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[[Category: Old Yellow Enzyme]] | [[Category: Old Yellow Enzyme]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Protein structure initiative | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Refinement methodology development]] | [[Category: Refinement methodology development]] | ||
[[Category: Secondary messenger]] | [[Category: Secondary messenger]] | ||
[[Category: Xenobiotic reductase]] | [[Category: Xenobiotic reductase]] | ||