3el3: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3el3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3el3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3el3 RCSB], [http://www.ebi.ac.uk/pdbsum/3el3 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3el3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3el3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3el3 RCSB], [http://www.ebi.ac.uk/pdbsum/3el3 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q9K498_STRCO Q9K498_STRCO]] Involved in the biosynthesis of the sesquiterpenoid antibiotic albaflavenone. Catalyzes the two-step allylic oxidation of epi-isozizaene to albaflavenone. First carries out a non-stereo-specific oxidation of epi-isozizaene to give a mixture of the albaflavenol epimers ((5R)-albaflavenol and (5S)-albaflavenol), each of which can serve as substrate for the second oxidation to yield albaflavenone. This is quite different from most other P450s which catalyze regio- and stereospecific oxidation. Displays also a farnesene synthase activity with farnesyl diphosphate (FPP) as substrate.<ref>PMID:18234666</ref> <ref>PMID:19858213</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
